Analogue Circuit Control through Gene Expression

نویسندگان

  • Kester Clegg
  • Susan Stepney
چکیده

Software configurable analogue arrays offer an intriguing platform for automated design by evolutionary algorithms. Like previous evolvable hardware experiments, these platforms are subject to noise during physical interaction with their environment. We report preliminary results of an evolutionary system that uses concepts from gene expression to both discover and decide when to deploy analogue circuits. The output of a circuit is used to trigger its reconfiguration to meet changing conditions. We examine the issues of noise during our evolutionary runs, show how this was overcome and illustrate our system with a simple proof-of-concept task that shows how the same mechanism of control works for progressive developmental stages (canalisation) or adaptable control (homoeostasis). 1 Background and motivation We present a system for the automated discovery and deployment of software configured analogue circuits. High level circuit components (for example, analogue filters) are modelled as ‘genes’. Genes are ‘expressed’ in response to circuit output; as conditions change new genes are expressed, triggering the deployment of a new circuit. Gene characteristics are defined in a genome representation discovered using evolutionary algorithms. Evolutionary computation has a proven record as a technique for searchbased optimisation [1–3]. The method has also been used to automate design discovery [4, 5]. To date most work in the field focuses on the performance of evolutionary search. Fewer researchers are questioning the precepts on which stochastic, population-based algorithms are founded, whether their evolutionary model corresponds to modern biological thinking [6] or the role of developmental processes in evolution [7]. The latter is particularly important with regard to how gene expression explores the functional search space [8]. Thompson’s ground-breaking work in the mid-1990s established that search algorithms could be used to discover novel hardware configurations that lie outside conventional engineering knowledge [9]. Thompson concentrated on innovation rather than rapid discovery, and was careful to design his experiments so that the search could exploit physical characteristics not normally incorporated into an engineer’s design [10]. Following on from this, further examples using evolutionary algorithms in software configured physical media have come from

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evaluation the effect of analog curcumin on the display and expression of SIRT1 and FAS genes in HepG2 fatty cells.

Abstract: Background: Non-alcoholic fatty liver is a disease that will lead to liver cirrhosis if not treated. Curcumin is the active substance of the rhizome of the turmeric plant, which has antioxidant, anti-inflammatory, antimicrobial, etc. properties. In the present study, the effects of curcumin analogue on the expression of SIRT1 and FAS genes and the accumulation of triglycerides in f...

متن کامل

اثر هشت هفته تمرین‌های دایره‌ای بر بیان ژن AGRP لنفوسیت کشتی‌گیران تمرین‌کرده

Background and Objective: Agouti-related protein (AGRP) is an orexigenic peptide and found to be secreted from hypothalamic arcuate nucleus (ARC) and has important role in appetite and food intake. It has been shown that AGRP has an important role in weight control and plasma levels of this peptide increases in fatness and starvation. The aim of this study was to study the effect of 8-weeks cir...

متن کامل

MOLECULAR ANALYSIS OF THE SULFUR REGULATORY CIRCUIT OF NEUROSPORA CRASSA

The sulfur regulatory circuit of the filamentous fungus, Neurospora crassa, consists of a set of unlinked structural genes which encode sulfur catabolic and two major regulatory genes which govern their expression. The cys-3 regulatory gene encode a transacting regulatory protein which activates the expression of cys-14 and ars, whereas the other regulatory genes Scon-l and Scon-2 appear to...

متن کامل

Bisphenol-A analogue (bisphenol-S) exposure alters female reproductive tract and apoptosis/oxidative gene expression in blastocyst-derived cells

Objective(s): One of the major endocrine-disrupting chemicals, Bisphenol-S (BPS) has replaced bisphenol-A due to public health anxiety. The present study evaluated low dosage BPS effect on female reproductive potential, hormonal disruption, and gene expression pathways of blastocyst-derived cells.Materials and Methods: NMRI female mice (...

متن کامل

بررسی اثر هشت هفته تمرین هوازی بر اشتها و گرلین آسیل دار پلاسمای زمان استراحت و ناشی از ورزش وامانده‌ساز در مردان دانشجو

Background and Objective: Agouti related protein (AGRP) is an orexigenic peptide and found to be secreted from hypothalamic arcuate nucleus (ARC) and has important role in appetite and food intake. It has been shown that AGRP has an important role in weight control and plasma levels of this peptide increases in fatness and starvation. The aim of this study was studding the effect of 8 weeks of ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2008